HANGZHOU TIANYE CHEMICALS CO., LTD.
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Tel: 0571-85083592
Tel: 0571-85085803
Tel: 0571-87065260
Mobile: 18658191951
Tel: 0571-85083592
Fax: 0571-85085803
Province/state: Zhejiang
City: Hangzhou
Street: 1208# HuaCe Building-B,Wuchanggang Road,XIHU District,Hangzhou City,Zhejiang Province ,China
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CAS NO.446-72-0
| Product Name: | Genistein |
| Synonyms: | 4’,5,7-trihydroxy-isoflavon;prunetol;sophoricol;5,7,4'-TRIHYDROXYISOFLAVONE;5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE;5,7-DIHYDROXY-3-(4-HYDROXY-PHENYL)-CHROMEN-4-ONE;AKOS NCG1-0029;GENISTEIN |
| CAS: | 446-72-0 |
| MF: | C15H10O5 |
| MW: | 270.24 |
| EINECS: | 207-174-9 |
| Product Categories: | Inhibitors;Tyrosine Kinase Inhibitors;Natural Plant Extract;The group of Daidzin;Protein Kinase;Signalling;pharmacetical;Biochemistry;Flavonoids;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Plant extract;Herb extract;inhibitor;J's;446-72-0;john's |
| Mol File: | 446-72-0.mol |
| Uses | It has anti-tumor, anti-fungal, blood lipid-lowering and can fight against estrogen activity. |
| Uses | genistein is an isoflavone commonly found in soy. It has demonstrated uV-protection properties through anti-oxidant activity. Studies indicate genistein can promote collagen synthesis, making it applicable in anti-aging cosmetics. |
| Uses | Exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol |
| Uses | Genistein, a phytoestrogen found in soy products, is a highly specific inhibitor of protein tyrosine kinase (PTK) which blocks the mitogenic effect mediated by EGF on NIH-3T3 cells with IC50 of 12μM or by insulin with IC50 of 19 μM. |
| Uses | cytotoxic inhibitor of tyrosine kinase and topoisomerase II kinase |
HANGZHOU TIANYE CHEMICALS Co.LTD , Located in Eastern Science and Innovation Park Hangzhou .
We are a high-tech enterprise specialized in technical research and development, production, development and trade of chemical products.
We supply Multiple solutions for our customers include offering, research ,Contract Manufacturing Organization(CMO),Contract development and manufacturing organization(CDMO) .
We have obtained ISO 9001 and ISO 14001 certificates to make sure supply more superior quality and Environmentally friendly chemicals .
Since 2009, we have provided various chemical products to customers around the world, And We practice the concept of "customer first" and hope to provide customers with all-round and high-quality services and will keep it all the time .
We are willing to become your trustworthy partner with high-quality products and sincere service!
We can provide customers with small quantities with gram level for laboratories research to tonnage level for industrial production Synthesis capacity from 1 liter to 5000 liter is available.